Helicobacter pylori infection in Iran: demographic, endoscopic and pathological factors

Abstract Background Helicobacter pylori ( H. ) infection is the most important risk factor for gastritis and peptic ulcer. However, factors other than are involved in its pathogenesis. In current study, we aimed to compare clinical manifestations endoscopic histopathological findings of patients with without infection. Methods this cross-sectional 233 dyspepsia, referred endoscopy, were examined regarding presence During an exam , 5 biopsy specimens taken from stomach . The criteria was identification bacteria pathology. Two groups -positive -negative compared their demographic, endoscopic, pathological findings. Results Of patients, 154 (66.1%) non-smokers, 201 (86.3%) not alcohol users, 153 (65.7%) used tap water. common symptom, reported 157 (67.4%) epigastric pain. There a significant difference between terms educational status, occupational family history gastrointestinal cancer, some symptoms. Also, there relationship Conclusions results present study revealed that associated sex, consumption, or non-steroidal anti-inflammatory drug use. role pathophysiology ulcer clarified.